What are oligoclonal striations and why it is worth knowing

Nowadays, the diagnosis of many diseases is at a very advanced level. Nowadays, samples of serum or cerebrospinal fluid are enough to confirm neurological diseases.
The oligoclonal striations contained in it can tell us a lot about our health condition – among other things, to confirm or exclude the disease.
So let’s check what they are and what diseases help to detect the test to determine the oligoclonal striations.
What are oligoclonic striations?
Oligoclonic bands are proteins that appear in the cerebrospinal fluid after breaking the blood-brain barrier. The presence of oligoclonal striations in cerebrospinal fluid usually means multiple sclerosis. However, it may also be a sign of other diseases such as encephalitis of different origin and character, syphilis of the nervous system or other infectious and autoimmune diseases. Therefore, a positive result indicating their presence means that the patient must be closely monitored and further diagnosed. Among other things, the IgG index should be tested. An elevated result may mean that immunological processes take place within the central nervous system. If you are interested in this topic, learn more about oligoclonal striations.
What does the test for ribbon presence look like?
As the name suggests, it is necessary to collect cerebrospinal fluid. However, you should not be afraid of it. Currently, this test is performed by taking a sample from the patient’s spine. To do this, a needle must be inserted between the vertebrae. However, it is not painful because the patient is locally anaesthetized. In order for the examination to take place, the patient must take the appropriate position – shrink his legs to the chest.
Where else can they appear?
At this point it is worth mentioning that oligoclonal proteins can appear not only in the cerebrospinal fluid, but also in the blood serum. Therefore, sometimes doctors order a test for the presence of striations from a blood sample. This examination, combined with magnetic resonance imaging and examination of visual evoked potentials, effectively allows to diagnose multiple sclerosis.
Oligoclonal striations were found – what next?
Unfortunately, the presence of oligoclonal striations is most often a confirmation of multiple sclerosis. Fortunately, nowadays there are many drugs that significantly slow down the development of the disease. So don’t break down. Patients with multiple sclerosis, who are under good medical care maintain their fitness for many years.
To sum up, tests aimed at detecting the presence of oligoclonal protein in serum or cerebrospinal fluid are one of the most effective tests allowing to confirm or deny multiple sclerosis and other neurological diseases. It is not surprising, therefore, that nowadays more and more doctors, seeing suspicious symptoms and ailments, are commissioning this examination.